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A fatal crash involving a tractor-trailer is causing major delays on Route 222 in Lancaster County.

The crash happened shortly after 4 a.m. in the northbound lanes of 222 about a mile south of the Denver Turnpike exit.

Northbound traffic is down to one lane and is expected to remain that way for hours (as of 10:30 a.m.).

The tractor-trailer was carrying construction equipment. It's not yet known what caused the crash.