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Route 272 in Lancaster County near Willow Street is open following a fatal crash early Monday involving mules and three vehicles.

The crash happened about 6 a.m. Monday when two mules were struck in the southbound lanes just south of Willow Street.

The vehicle that struck the mules crossed into the northbound lanes and was hit by two vehicles.

The 19-year-old male driver of the vehicle that struck the mules was killed. One of mules was killed and the other was injured and later put down.