Highway 281

San Antonio, TX

Yareli Salas Dominguez, 22, Leslie Salas Dominguez, 25, and one person killed in rear-end crash on Highway 281 in San Antonio, Texas

Accident Date:

Fri, 11/22/2024

Central Texas

32-year-old pedestrian was struck and killed by a hit-and-run driver on Highway 281 in Comal County, Texas

Accident Date:

Thu, 01/30/2020

Central Texas

One killed in a two-car head-on collision on Highway 281 in Comal County, Texas

Accident Date:

Thu, 11/22/2012

Harlingen-Weslaco-Brownsville-McAllen, TX

Roberto Carlos Robles, 46, died in two-vehicle wrong-way crash on Highway 281 in Hidalgo County, Texas

Accident Date:

Thu, 04/20/2023

Fargo-Valley City, ND

64-year-old passenger killed, driver seriously injured when their truck's trailer is blown off by wind, causing collision with semi truck on Highway 281 near Edgeley, North Dakota

Accident Date:

Sun, 11/06/2022

Fargo-Valley City, ND

UPS driver Ross Bergquist, 37, killed in collision with fuel tanker on Highway 281 in Jamestown, North Dakota

Accident Date:

Tue, 09/20/2022

Harlingen-Weslaco-Brownsville-McAllen, TX

Several people injured and Manuel Hernandez Jr. arrested following crash during police pursuit on Highway 281 in Brownsville, Texas

Accident Date:

Tue, 03/01/2022

Fargo-Valley City, ND

Two injured in crash on Highway 281 in Jamestown, North Dakota

Accident Date:

Fri, 12/31/2021

Harlingen-Weslaco-Brownsville-McAllen, TX

Alex Jaramillo, 20, and Efrain Guerrero Jr., 31, killed in wrong-way collision on Highway 281 in Edinburg, Texas

Accident Date:

Sun, 06/27/2021

Harlingen-Weslaco-Brownsville-McAllen, TX

Agent injured in pedestrian collision during immigration inspection on Highway 281 near San Manuel, Texas

Accident Date:

Thu, 12/03/2020

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