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The southbound lane of Interstate 65 was closed near Atmore late Sunday after at least two people were killed and one critically injured in a multi-vehicle accident involving an 18-wheeler.
According to the Alabama Highway Patrol, the southbound lane will remain closed until around 10:30 a.m. Traffic is being rerouted at the 54 mile marker.
The Poarch Creek Tribal Police Department received the first call about an accident at the 51 mile marker at about 10:45 p.m. Sunday night, a dispatcher there said.
Two children from North Carolina died in a five-vehicle crash in southwest Alabama.
State troopers said 7-year-old Naziya Gillis and 9-year-old Nadir Gillis of Camp LeJune, N.C., were killed when the Dodge Challenger in which they were riding was struck by a tractor-trailer truck.
The driver of the Dodge, 28-year-old Isom Hodges, and a passenger, 30-year-old Labricia Hodges, both of Camp LeJune, were injured. The driver of another car, 42-year-old William Rousey of Lexington, Ky., was also injured. No other drivers, including the truck driver, were injured.