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Two 14-year-olds and a 25-year-old woman suffered serious injuries in a high-speed crash in Des Moines on Saturday. At about 3 p.m. Des Moines police responded to a two-vehicle collision in the intersection of South 240th Street and 20th Avenue South.Investigators said the vehicle that caused the crash was travelling southbound at a high rate of speed on 20th Avenue South, ran a stop sign and struck the other vehicle, which was traveling eastbound on South 240th Street.