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A 45-year-old Canonsburg man was killed and two others were injured in a crash involving a tractor-trailer and two cars on Interstate 70 south in South Strabane Township on Saturday afternoon, officials said. Brian J. Anselmino was driving east when a car traveling west lost control, crossed the median and hit Anselmino’s car head-on around 1 p.m. in Washington County, officials said. A passenger in Anselmino’s car was taken to Pittsburgh Hospital. Two other vehicles were involved in the crash. I-70 was closed in both directions between mile marker 20 and 21 after the crash, officials said.