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The westbound lanes of Interstate 80-94 were shut down on Wednesday when a semi slid off the road.
The accident happened near Ripley street in Lake Station.
State Police have been warning that roads are slick after about seven inches of snow fell across Northwest Indiana overnight.
All westbound lanes were blocked.
Camera images from the area showed portions of the road were snow-covered.
There were multiple accidents along Lamar Avenue in Memphis due to icy road conditions. At least one person was thrown from a vehicle and rushed to the hospital.
Reports are that a car has overturned at Lamar Avenue at Winchester Road. There is another accident on Lamar Avenue at East Holmes Road.
A third accident has been reported at Old Lamar Avenue at Perkins Road that involves at least six vehicles. Witnesses on the scene said that it appears the vehicles hit patches of ice and wrecked.
An Alabama Department of Corrections employee was one of the people killed in traffic accidents on icy roads this week.
Corrections Officer Desi Arnez Patterson, 43, was killed Thursday in a wreck on U.S. Highway 82 in southern Chilton County.
Patterson was on his way from his home in Montgomery to work at the Bibb County Correctional Facility in Brent, according to a news release from ADOC spokesman Brian Corbett. He started at the Department of Corrections in August of 1998.
A Montgomery man was killed Thursday when his vehicle left an icy roadway in southern Chilton County and hit a tree, according to Alabama State Troopers.
Desi Patterson, 43, was killed in the single-vehicle wreck on U.S. 82 about four miles west of Billingsley around 5 a.m., according to Alabama State Troopers spokesman Sgt. Steve Jarrett.
The road was icy and Patterson was not wearing a seat belt during the crash, Jarrett said.
Troopers continue to investigate.