On Saturday evening, just after 9:00 p.m., a tragic single-vehicle accident occurred on Highway 45, north of County Trunk Y in the Township of Oshkosh, Wisconsin, resulting in one fatality.

A significant traffic incident occurred on Tuesday, April 15, when an 18-wheeler overturned on Highway 45 Southbound near McCullough Boulevard in Tupelo, Mississippi, causing extensive traffic disruptions.

A devastating head-on collision on Highway 45 near County Highway Y in the town of Auburn, Fond du Lac County, resulted in the death of a 26-year-old West Bend man and left a 16-year-old Campbellsport girl with serious injuries on Friday, December 13, 2024.