Lisa Marie Hough, 40, killed in wrong-way hit-and-run collision on Interstate 77 in Cayce, South Carolina

The Nissan hit a Chevrolet SUV at the intersection and fled the scene of that collision at a high rate of speed. The Nissan then continued to go the wrong direction on the I-77 exit ramp and struck a 2012 Dodge 4500 truck almost head on, disabling both vehicles.