U.S. 421

Indianapolis, IN

Semi-Truck Rollover Accident on U.S. 421 in Decatur County, Indiana Results in Road Closure

Accident Date:

Fri, 01/31/2025

On Friday morning, a significant traffic incident occurred on U.S. 421 at its intersection with County Road 550 East in Decatur County, Indiana, when a semi-truck was forced to take evasive action after another vehicle pulled into its path.

Cincinnati, OH

Nathan Vogelsang, 24, and Landon J. W. Comer, 19, killed in collision involving semi truck on U.S. 421 near Versailles, Indiana

Accident Date:

Tue, 11/26/2024

Greensboro-High Point-Winston Salem, NC

Virginia Wood, 89, died following a rear-end collision involving a car and a UPS truck on U.S. 421 in Winston-Salem, North Carolina

Accident Date:

Thu, 09/28/2023

Cincinnati, OH

Several hospitalized following a collision between a car and a buggy on U.S. 421 in Ripley County, Indiana

Accident Date:

Sun, 09/10/2023

Cincinnati, OH

One injured in a single-vehicle rollover crash on U.S. 421 in Versailles, Indiana

Accident Date:

Sun, 08/27/2023

Greensboro-High Point-Winston Salem, NC

One killed and one hurt following plane crash on U.S. 421 in Guilford County, North Carolina

Accident Date:

Tue, 04/11/2023

Indianapolis, IN

Noah Seals, 26, killed, and Patrick Stroud, 38, injured, in head-on crash on U.S. 421 in Decatur County, Indiana

Accident Date:

Mon, 02/06/2023

Louisville, KY

Charles J. Hunter Jr., 23, killed and Antonio Lopez, 64, injured after their vehicles collide head-on on U.S. 421 near Madison, Indiana

Accident Date:

Fri, 04/01/2022

Cincinnati, OH

Two hospitalized, including one who was airlifted after two-vehicle crash leaves two trapped in car on U.S. 421 near Rexville, Indiana

Accident Date:

Sat, 02/26/2022

Cincinnati, OH

Norman Kappes, 53, dies after his car crosses center-line and strikes dump truck on U.S. 421 near Napoleon, Indiana

Accident Date:

Sat, 01/29/2022

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